Genomic Sciences and Biotechnology

Area of Concentration: GENOMIC SCIENCES

Lines of research

MOLECULAR BIOLOGY OF MICROORGANISMS, PLANTS AND ANIMALS

Organization of genetic material in prokaryotes and eukaryotes. Gene structure and characterization. Genetic manipulation of microorganisms. Transcriptoma and gene expression analysis. Non-coding RNAs and regulation. Host-pathogen interaction. Gene prospecting and analysis. Proteins related to defenses in animals and plants.

GENOMICS OF MICROORGANISMS, PLANTS, AND ANIMALS

Structural and functional genome mapping. Eukaryotic and prokaryotic genome structure. Assembling contigs. Sequence analysis in databases and annotation. Availability of genomic data.

Concentration Area: MOLECULAR AND CELLULAR BIOTECHNOLOGY

Lines of research

BIOINFORMATICS APPLIED TO GENOMICS AND PROTEOMICS

Biological sequence analysis. Assembly and Annotation of Genomes and Metagenomes. Transcriptomics and Identification of Genetic Variations. Phylogenetic tree. Search in databases. Construction of biological databases. Structural Bioinformatics, Modeling, Docking and Molecular Dynamics. Prediction of secondary and tertiary structure of proteins.

BIOTECHNOLOGY/NANOTECHNOLOGY APPLIED TO HUMAN, ANIMAL, PLANT AND ENVIRONMENT HEALTH

Identification of new antimicrobial, anti-tumor and anti-aging bioactive molecules, nanostructuring of bioactive molecules, characterization of biocompatible and biodegradable nanostructures. Development of products/processes applied to human, animal, plant and environmental health.

ENTREPRENEURSHIP, INTELLECTUAL PROPERTY AND BUSINESS MANAGEMENT IN BIOTECHNOLOGY

How to start a biotechnology business, Challenges to structure a startup in biotechnology, Intellectual Property Management. National and international legislation. Search for patents in national and international databases. Patent drafting. Regulatory for biotechnology products and processes applied to human, animal, plant and environmental health.

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General Infrastructure

The PPG Biotechnology Laboratory in Genomic Sciences and Biotechnology is located in Block G, Taguatinga campus, with about 900 m2 divided into 3 large areas: Area 1: Preparation and cultivation, with weighing room and solution preparation, cold room, decontamination and sterilization rooms, area for experiments with animal and vegetable cells, microorganisms levels 1 and 2 of biosafety and microscopy. Area 2: Molecular Biology, Area 3: Highly complex laboratories. Area 4: Bioinformatics Laboratory, on the other hand, is located in Block K. All spaces and equipment are multi-user and subject to prior appointment. Access to the laboratories is controlled by a biometric system, authorized for previously registered and trained users. See images of the laboratories and more details.

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Area 1: Crop preparation

It is the general support laboratory for the activities in the program. It concentrates the basic equipment necessary for the development of biotechnology research activities, such as a weighing room and solution preparation, sterilization and decontamination room and unidirectional flow, cell culture room, plant cultivation room, room for manipulation and cultivation of microorganisms (Biosafety levels 1 and 2) in addition to storage, cold room and ultrafreezer room and microscopy room.

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Area 2: Molecular Biology Laboratory

This space has workbenches with a capacity for at least 30 people and is intended for working with DNA and RNA. It has equipment for DNA amplification (thermocyclers), agarose electrophoresis devices, photodocumenters, nucleic acid quantifiers, dry baths and other equipment to support these techniques. In addition to a room dedicated exclusively to RNA extraction and manipulation.

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Area 3: Highly Complexity Laboratories

Bioprocesses and scaling laboratory

This space brings together equipment used for experiments involving the transformation and expression of heterologous proteins and peptides, production of natural bioactive molecules on a laboratory scale and on a pilot scale. It has bioreactors with a capacity of 1, 3, 5 liters and 10 liters, a photobioreactor for growing plant cells and a bioreactor with a capacity of 120 L, an autoclave of 225 L.

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Molecular Purification and Mass Spectrometry Laboratory

Equipped with a water purification system, exhaust hood, four High Efficiency Liquid Chromatographs (HPLC), an Akta Avant purification system, and two Bruker mass spectrometers (MALDI and ESI). It also has a structure for protein extraction and analysis, electrophoresis devices, a lyophilizer and speed vacum. In addition to an electrospin for the production of nanofibers

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Sequencing Laboratory

The laboratory has an ABI3130 XL capillary electrophoresis sequencer and a MiSeq Illumina next-generation sequencer, Bioanalyzer, and digital PCR. In addition to equipment and accessories to meet these techniques.

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Area 4: Bioinformatics Laboratory

The space has a structure of 9 workstations that are used for data analysis and database construction. In addition to these workstations, it also has a “Next Generation Sequencing” sequence analysis server, Large-scale Sequencing Data Analysis (Assembly and Annotation of Genomes and Metagenomes) Differential Expression Analysis, Transcritomic Characterization and Identification of Genetic Variations), Structural Bioinformatics Tools (Modeling, Docking and Molecular Dynamics) for protein stability studies and for analysis of the impact of specific variations in protein structures.

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The scheduling of technical visits, collaborations and the development of experiments in our spaces can be requested by e-mail: labbiotecnologia@ucb.br

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Gross monthly fee: 24 x R$ 3,043.65*

Monthly fee with Business Discount: 24 x R$ 2,130.55**

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*Values for the year 2025.

**Consult conditions with the sales team.

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Check out the matrix of the Stricto Sensu Graduate Program in Genomic Sciences and Biotechnology at UCB.

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